Restricted access barrier systems for aseptic processing of pharmaceutical products reduces and eliminates interventions into the critical zone through 

Rigid wall enclosure with interlocked doors, Unidirectional air flow systems reaching grade A environment in the critical area, Using glove ports and half suits to access all areas of the enclosure during operations to minimize exposure to personnel, as well as Maintaining High level of asepsis through unidirectional air flow with High Efficiency Filters, while monitoring of the internal particle contamination through particles counting equipment in addition to the use of over pressure to ensure the integrity of the working through those procedures microbial or particulate contamination risk is minimized inside the core working area.